Animal care

For livestock, our IgY applications focus on supporting the animals’ gastrointestinal health and, thus, enhancing their performance

Thanks to decades of research on maternal immunity mechanism, IRIG has successfully developed many patented IgY applications against different pathogens in human and animals.

Focus areas

IgY for piglets

Diarrhea is the most important disease affecting piglets, causing death and poor performance. As the causative agents of diarrhea consist of various bacteria, viruses, parasites, etc., its control in the farms is very difficult. For more than two decades, we have proven that IgY can be useful in preventing diarrhea and improving piglets’ performance.

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IgY for calves

Like piglets, newborn calves frequently suffer from diarrhea and subsequent death due to various infectious agents in the gastrointestinal tract. These include bacteria, viruses, and protozoa. More than 20 years ago our institute was the first to demonstrate that IgY specifically prepared against E. coli and rotaviruses could be used to control these infections in newborn calves.
Our research has shown that specific combinations of different IgY can help the animals grow better.

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Related publications

IgY-based Innovations for Animal Health


Title: IgY-based Innovations for Animal Health Date: July 2025 Description: We are excited to present a set of new resources developed in collaboration with IRIG and EW Nutrition. These publications focus on the use of immunoglobulin Y (IgY) in both livestock and pet health. Podcast: Dr. Shofiqur Rahman: IgY in Pet Health Download: Handbook on…

Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases


Title: Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases Date: Jan. 2013 Book : Advances in Medicine and Biology. Volume 65 (2013 Nova Science Publishers, Inc.) Chapter 6: Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases, p 119-137. Download: APPLICATION OF THE EGG YOLK IMMUNOGLOBULIN (IGY) TO GASTROINTESTINAL INFECTIOUS…

Egg Yolk Antibody-IgY


Title: Egg Yolk Antibody-IgY Date: 12th Sep. 2023 Book : Handbook of Egg Science and Technology (CRC Press) Chapter 27: Egg Yolk Antibody-IgY, p 496-565. Download: Handbook of Egg Science and Technology

Egg Yolk Antibody-IgY


Title: Egg Yolk Antibody-IgY Date: 12th Sep. 2023 Book : Handbook of Egg Science and Technology (CRC Press) Chapter 27: Egg Yolk Antibody-IgY, p 496-565. Download: Handbook of Egg Science and Technology

Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases


Title: Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases Date: Jan. 2013 Book : Advances in Medicine and Biology. Volume 65 (2013 Nova Science Publishers, Inc.) Chapter 6: Application of the Egg Yolk Immunoglobulin (IgY) to Gastrointestinal Infectious Diseases, p 119-137. Download: APPLICATION OF THE EGG YOLK IMMUNOGLOBULIN (IGY) TO GASTROINTESTINAL INFECTIOUS…

Anti-lipopolysaccharide IgY reduce rumen acidosis in cattle.


Title: Anti-lipopolysaccharide antibody administration mitigates ruminal lipopolysaccharide release and depression of ruminal pH during subacute ruminal acidosis challenge in Holstein bull cattle Date: 2021 Journal: J. Vet. Med. Sci. 83(6): 905–910, 2021 doi: 10.1292/jvms.21-0037 Link: Anti-lipopolysaccharide antibody administration mitigates ruminal lipopolysaccharide release and depression of ruminal pH during subacute ruminal acidosis challenge in Holstein bull…

Molecular Epidemiological Analysis of Bovine Rotaviruses


Title: Development of Genotype-Specific Anti-Bovine Rotavirus A Immunoglobulin Yolk Based on a Current Molecular Epidemiological Analysis of Bovine Rotaviruses A Collected in Japan during 2017–2020 Date: December 2020 Journal: Viruses, Dec 3; 12 (12), 1386- (2020) doi: 10.3390/v12121386. Link: https://doi.org/10.3390/v12121386

Immunoglobulins boost weaner performance


Title: Immunoglobulins boost weaner performance Date: July/August 2020 Journal: Asian Pork Magazine, 2020 July/August; 20-22 Download: PP_Jul2020_Immunoglobulins boost weaner performance

IgY gives calves boost


Title: Egg powder gives calves boost Date: 2020 Journal: All About Feed 18-11, 2020 (Source: Feed Mix vol 17 nr 6, 2009) Link: Egg powder gives calves boost – All About Feed  

Supporting the immune system of piglets


Title:  Supporting the immune system of piglets Date: 2016 Journal: Asian Pork Magazine 2016, Jan/Feb: 24-27 Download:AC-25 2016.1 Asian Pork Magazine EWNG piglet

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IRIG: Immunology Research Institute, Gifu - Japan