Animal care

For livestock, our IgY applications focus on supporting the animals’ gastrointestinal health and, thus, enhancing their performance

Thanks to decades of research on maternal immunity mechanism, IRIG has successfully developed many patented IgY applications against different pathogens in human and animals.

Focus areas

IgY for piglets

Diarrhea is the most important disease affecting piglets, causing death and poor performance. As the causative agents of diarrhea consist of various bacteria, viruses, parasites, etc., its control in the farms is very difficult. For more than two decades, we have proven that IgY can be useful in preventing diarrhea and improving piglets’ performance.

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IgY for calves

Like piglets, newborn calves frequently suffer from diarrhea and subsequent death due to various infectious agents in the gastrointestinal tract. These include bacteria, viruses, and protozoa. More than 20 years ago our institute was the first to demonstrate that IgY specifically prepared against E. coli and rotaviruses could be used to control these infections in newborn calves.
Our research has shown that specific combinations of different IgY can help the animals grow better.

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Related publications

Avidity of IgY to ETEC Fimbriae


Title: Research note: Avidity of Chicken Yolk Antibodies to Enterotoxigenis Escherichia coli Fimbriae Date: 1993 Journal: Poultry Science 1993, 72 : 2361-2365 Link: Research Note: Avidity of Chicken Yolk Antibodies to Enterotoxigenic Escherichia coli Fimbriae (sciencedirectassets.com)

Passive protection against bovine rotavirus-induced diarrhea in murine model by IgY


Title: Passive protection against bovine rotavirus-induced diarrhea in murine model by specific immunoglobulins from chicken egg yolk Date: 1993 Journal: Veterinary Microbiology 1993, 37: 135-146 Link: Passive protection against bovine rotavirus-induced diarrhea in murine model by specific immunoglobulins from chicken egg yolk – ScienceDirect

Passage and absorption of IgY in the gastrointestinal tract of pigs


Title: Detection of passage and absorption of chicken egg yolk immunoglobulins in the gastrointestinal tract of pigs by use of enzyme-linked immunosorbent assay and fluorescent antibody testing Date: 1993 Journal: American Journal of Veterinary Research 1993, 54(6): 867-872 Link: Detection of passage and absorption of chicken egg yolk immunoglobulins in the gastrointestinal tract of pigs…

Protection of calves against enteric colibacillosis by administration of IgY with ETEC


Title: Protection of neonatal calves against fatal enteric colibacillosis by administration of egg yolk powder from hens immunized with K99-piliated enterotoxigenic Escherichia coli Date: 1992 Journal: American Journal of Veterinary Research 1992, 53(11): 2005-2008 Link: Protection of neonatal calves against fatal enteric colibacillosis by administration of egg yolk powder from hens immunized with K99-piliated enterotoxigenic…

Passive Protective effect of IgY against ETEC Infection in Piglets


Title: Passive Protective effect of Chicken Egg Yolk Immunoglobulins against Experimental Enterotoxigenic Escherichia coli Infection in Neonatal Piglets Date: 1992 Journal: Infection and Immunity 1992, 60(3): 998-1007 Link: Passive protective effect of chicken egg yolk immunoglobulins against experimental enterotoxigenic Escherichia coli infection in neonatal piglets (asm.org)  

Adaptation of transmissible gastroenteritis virus in cells


Title: Adaptation of transmissible gastroenteritis virus to growth in non-permissive Vero cells Date: 1992 Journal: Archives of virology 1992, 122: 201-206 Link: Adaptation of transmissible gastroenteritis virus to growth in non-permissive Vero cells (springer.com)

Purification of Pili from ETEC by Affinity Chromatography


Title: Purification of K88 and K99 Pili from Porcine Enterotoxigenic Escherichia coli by Affinity Chromatography Date: 1988 Journal: Japanese Journal of Veterinary Science  1988, 50(4): 951-953 Link: _pdf (jst.go.jp)  

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IRIG: Immunology Research Institute, Gifu - Japan