飼料等論文

飼料等論文Scientific Articles

様々な研究機関との共同研究や独自の研究により得られた成果を学会誌に投稿し、学術的エビデンスを得ています。

＜乳酸菌＞Lactic acid bacteria

抗生より共生（機能性飼料）(和)

Symbiosis rather than antibiotics (Functional feed)

家畜診療2004, 51(2): 69-77

横山英明ら

抗生物質の進歩は1929年のペニシリンの発見に始まり，人類を苦しめてきた多くの感染症の治療に力を発揮した。しかしその影の部分として，メチシリン耐性プドウ球菌(MRSA)やバンコマイシン耐性腸球菌(VR E ) などの薬剤耐性菌の問題を生じ，抗生物質療法の限界を示す深刻な問題を抱えるに至った。21世紀は予防獣医学の比重が増し，防御システムの見直しが課題となる。生体防御システムとしての免疫と腸内細菌叢(floraまたはbiota)の意義を捉えたものがプロバイオティクスであり，また発展した飼料が機能性飼料である。

Enhancement of chicken resistance against Escherichia coli infection by oral administration of Bifidobacterium thermophilum preparations

ビヒドバクテリウム・サーモフィルム菌の経口投与によって大腸菌感染症に対する鶏の抵抗の改良

Avian Diseases 2002, 46:542-546

Chizu Kobayashi, et al.

https://www.jstor.org/stable/1592932?seq=1#page_scan_tab_contents

Three types of Bifidobacterium thermophilum extract were prepared and fed to 2-wk-old chickens to evaluate their usefulness in enhancing the defense activity of the chickens against pathogenic Escherichia coli. All three preparations resulted in significant reduction (P < 0.05) of E. coli numbers in the lungs of the treated chicken groups compared with the control nontreated group. Besides, improvement in the survival rate was observed in the treated chicken groups, especially the one administered the enzyme-digested B. thermophilum extract sample. Concanavalin A-stimulated lymphocytes from the latter group demonstrated significantly higher proliferation activity compared with those from the control group. These results suggest that oral administration of B. thermophilum preparations may be used to enhance the resistance of chickens against E. coli infection.

Stress and intestinal flora

ストレスと腸内フローラ―の関係

Bifidobacteria Microflora 1989, 8(1):23-38

Kunio Suzuki, et al.: Frontier research Program, The Institute of Physical and Chemical Research (RIKEN)

https://www.jstage.jst.go.jp/article/bifidus1982/8/1/8_1_23/_article

https://www.jstage.jst.go.jp/article/bifidus1982/8/1/8_1_23/_pdf/-char/en

The effects of crowding and heat stress on the intestinal flora, body-weight gains, and feed efficiencies of rats and chickens as well as the effects of the administration of probiotics on the animals under stress were introduced. Irrespective of the type of stress and host species, the change of intestinal flora caused by stress showed almost the common tendency: when the animal suffered stress, Staphylococcus, Streptococcus，Corynebacterium, and Enterobacteriaceae commonly increased; when the stress was more severe, sometimes Peptococcaceae, Bacteroidaceae, and Clostridium also increased or Lactobacillus reduced. Body-weight gains and feed efficiencies were markedly suppressed under these stress conditions. Administering Lactobacillus to a chicken under heat stress improved its hypoplasia while administration of Bifidobacterium improved the feed efficiency and intestinal flora.